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Mir-938 microRNA precursor family : ウィキペディア英語版 | Mir-938 microRNA precursor family In molecular biology mir-938 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. ==miR-938 and the TGF-β pathway== miR-938 has been found to directly target the ''SMAD3'' gene, which encodes the main downstream TGF-β polypeptide SMAD3. This microRNA is overexpressed in non-functioning pituitary adenomas (NFPAs) compared with normal pituitary tissue.〔 〕 Downregulation of TGF-β signalling is likely to play a role in the regulation of signalling pathways in NFPA tumorigenesis, thus also implicating SMAD3 and miR-938.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mir-938 microRNA precursor family」の詳細全文を読む
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